Stryker’s acquisition of Amplitude Vascular Systems is valued at up to $835 million.
Stryker paid about $435 million up front to acquire Amplitude, the medical device maker said Monday in a regulatory filing. Terms of the deal, which closed last week, also include up to $400 million in future milestone payments.
In the filing, Stryker said it planned to integrate Amplitude into its vascular business within its MedSurg and Neurotechnology segment.
Amplitude is developing an intravascular lithotripsy platform designed to treat complex peripheral arterial disease. The Pulse IVL system uses pressure waves generated by carbon dioxide and delivered through a balloon catheter to break up calcified plaque and improve blood flow.
The investigational device is being evaluated in the POWER PAD II U.S. pivotal study.
The Amplitude acquisition follows Stryker’s approximately $4.9 billion purchase of Inari Medical, a maker of mechanical thrombectomy systems, in 2025.
With Pulse, Stryker is entering a fast-growing IVL market that has seen a burst of M&A over the past two years. Johnson & Johnson, which acquired Shockwave Medical for $13.1 billion in 2024, on Tuesday said it was launching a next-generation version of its IVL catheter to treat calcified coronary artery disease.
Abbott and Boston Scientific are also working to enter the IVL market.
